The core team at iNFixion Bioscience has successfully completed the prestigious NIH I-Corps™ commercialization program.  In addition to a commercialization curriculum, the program included teh requirement of conducting interviews with over 100 people from across the NF1 and Rare Drug ecosystems.  These interviews included: Adults with NF1, NF1 parents, NF clinic directors and specialists, rare disease and pharma professionals, and potential investment partners.  Using the I-Corps structure and methodology, the Infixion core team was able to crystallize its vision, improve their understanding of adult vs. pediatric requirements, establish a priority in terms of targeting NF1 symptoms, and solidify a tentative decision to pursue a companion biomarker program. The core team members also learned valuable presentation and teamwork skills while under the stress of conducting 106 half-hour interviews in just 7 weeks. 

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iNFixion Bioscience announced today its commitment to developing a new monoclonal antibody against NF1 protein. This NF1-specific reagent will be developed in rabbits using full-length NF1 protein as the immunogen, with the program goal being to establish a more sensitive and specific NF1 monoclonal antibody than is commercially available today. This NF1 research tool, once developed and validated, will be made available to the NF1 research community, on an at-cost basis.  This work is being developed in partnership with Abterra Biosciences (previously Digital Proteomics) and is financially supported by a partial grant from the NF Therapeutics Acceleration Program (NTAP).