Publications - Infixion Bioscience

iNFixion’s White Paper on NF1 Haploinsufficiency Correction Therapy (NF1-HCT)

Frost M, Serra E, Viskochil D, Korf BR, Mattson-Hoss MK, Croston GE, Sarnoff H. Rationale for haploinsufficiency correction therapy in neurofibromatosis type 1. J Transl Genet Genom. 2022;6:403-28.

Additional NF1 Publications with iNFixion Authors

Tomkinson J, Mattson C, Mattson-Hoss M, Sarnoff H, Bouley SJ, Walker JA, Way GP. High-content microscopy and machine learning characterize a cell morphology signature of NF1 genotype in Schwann cells. bioRxiv [Preprint]. 2025 Apr 10:2024.09.11.612546. doi: 10.1101/2024.09.11.612546. PMID: 40291747; PMCID: PMC12026412.
Chang M, Sherief M, Ioannou M, Chinnasamy V, Chen L, Frost M, Mattson-Hoss M, Sarnoff H, Kamson DO, Holdhoff M, Mukherjee D, Bettegowda C, Rincon-Torroella J, Croog V, Huang P, Rodriguez FJ, Lucas CG, Schreck KC. NF1 expression profiling in IDH-wildtype glioblastoma: genomic associations and survival outcomes. Acta Neuropathol Commun. 2024 Oct 29;12(1):172. doi: 10.1186/s40478-024-01875-z. PMID: 39472976; PMCID: PMC11520828.
Staedtke V, Anstett K, Bedwell D, Giovannini M, Keeling K, Kesterson R, Kim Y, Korf B, Leier A, McManus ML, Sarnoff H, Vitte J, Walker JA, Plotkin SR, Wallis D. Gene-targeted therapy for neurofibromatosis and schwannomatosis: The path to clinical trials. Clin Trials. 2024 Feb;21(1):51-66. doi: 10.1177/17407745231207970. Epub 2023 Nov 8. PMID: 37937606.
Sundby RT, Rhodes SD, Komlodi-Pasztor E, Sarnoff H, Grasso V, Upadhyaya M, Kim A, Evans DG, Blakeley JO, Hanemann CO, Bettegowda C. Recommendations for the collection and annotation of biosamples for analysis of biomarkers in neurofibromatosis and schwannomatosis clinical trials. Clin Trials. 2024 Feb;21(1):40-50. doi: 10.1177/17407745231203330. Epub 2023 Oct 31. PMID: 37904489; PMCID: PMC10922556.
Gross AM, Plotkin SR, Watts NB, Fisher MJ, Klesse LJ, Lessing AJ, McManus ML, Larson AN, Oberlander B, Rios JJ, Sarnoff H, Simpson BN, Ullrich NJ, Stevenson DA. Potential endpoints for assessment of bone health in persons with neurofibromatosis type 1. Clin Trials. 2024 Feb;21(1):29-39. doi: 10.1177/17407745231201338. Epub 2023 Sep 29. PMID: 37772407; PMCID: PMC10920397.

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iNFixion’s White Paper on NF1 Haploinsufficiency Correction Therapy (NF1-HCT)

Additional NF1 Publications with iNFixion Authors

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